Striatum morphometry is associated with cognitive control deficits and symptom severity in internet gaming disorder (2015))

Brain Imaging Behav. 2015 Feb 27. Cai C1, Yuan K, Yin J, Feng D, Bi Y, Li Y, Yu D, Jin C, Qin W, Tian J. Abstract Internet gaming disorder (IGD), identified in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) Section III as a condition warranting more clinical research, […]

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The role of dopamine in risk taking: a specific look at Parkinson’s disease and gambling (2014)

Front Behav Neurosci. 2014 May 30;8:196. doi: 10.3389/fnbeh.2014.00196. eCollection 2014. Crystal A. Clark and Alain Dagher* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract An influential model suggests that dopamine signals the difference between predicted and experienced reward. In […]

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Glutamatergic synaptic plasticity in the mesocorticolimbic system in addiction (2015)

Front Cell Neurosci. 2015 Jan 20;8:466. doi: 10.3389/fncel.2014.00466. eCollection 2014. van Huijstee AN1, Mansvelder HD1. Abstract Addictive drugs remodel the brain’s reward circuitry, the mesocorticolimbic dopamine (DA) system, by inducing widespread adaptations of glutamatergic synapses. This drug-induced synaptic plasticity is thought to contribute to both the development and the persistence of addiction. This review highlights […]

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Evidence for sugar addiction: behavioral and neurochemical effects of intermittent, excessive sugar intake (2008)

Neurosci Biobehav Rev. 2008;32(1):20-39. Epub 2007 May 18. Avena NM1, Rada P, Hoebel BG. Abstract The experimental question is whether or not sugar can be a substance of abuse and lead to a natural form of addiction. “Food addiction” seems plausible because brain pathways that evolved to respond to natural rewards are also activated by […]

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Which Foods May Be Addictive? The Roles of Processing, Fat Content, and Glycemic Load (2015)

Erica M. Schulte,  Nicole M. Avena, Ashley N. Gearhardt Published: February 18, 2015 DOI: 10.1371/journal.pone.0117959 Abstract Objectives We propose that highly processed foods share pharmacokinetic properties (e.g. concentrated dose, rapid rate of absorption) with drugs of abuse, due to the addition of fat and/or refined carbohydrates and the rapid rate the refined carbohydrates are absorbed […]

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Stress in adolescence and drugs of abuse in rodent models: role of dopamine, CRF, and HPA axis (2014)

Psychopharmacology (Berl). 2014 Apr;231(8):1557-80. doi: 10.1007/s00213-013-3369-1. Burke AR1, Miczek KA. Abstract RATIONALE: Research on adolescence and drug abuse increased substantially in the past decade. However, drug-addiction-related behaviors following stressful experiences during adolescence are less studied. We focus on rodent models of adolescent stress cross-sensitization to drugs of abuse. OBJECTIVES: Review the ontogeny of behavior, dopamine, […]

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Nicole Prause’s Unethical Harassment and Defamation of Gary Wilson & Others (Page 1)

Introduction Legal counsel advised us to create these pages, which document Nicole Prause’s extensive campaign targeting those who point out possible harms of porn use or issues in the porn industry. “Sunshine” protects the community Prause harasses by preserving facts and permitting visitors and journalists to understand the truth for themselves. Indeed, these pages have […]

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Common and distinct networks underlying reward valence and processing stages: A meta-analysis of functional neuroimaging studies (2011))

Published in final edited form as: Neurosci Biobehav Rev. 2011 Apr; 35(5): 1219–1236. Published online 2010 Dec 24. doi:  10.1016/j.neubiorev.2010.12.012 PMCID: PMC3395003 NIHMSID: NIHMS261816 Xun Liu,1,2 Jacqueline Hairston,2 Madeleine Schrier,2 and Jin Fan2,3,4 Author information ► Copyright and License information ► The publisher’s final edited version of this article is available at Neurosci Biobehav Rev […]

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Brain Reward and Stress Systems in Addiction (2014)

Front Psychiatry. 2014; 5: 79. Published online 2014 Jul 9. doi:  10.3389/fpsyt.2014.00079 PMCID: PMC4088186 Nicholas W. Gilpin1,* Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Addiction to drugs and alcohol is a dynamic and multi-faceted disease process in humans, with devastating health […]

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Human Striatal Response to Salient Nonrewarding Stimuli (2003)

J Neurosci. 2003 Sep 3;23(22):8092-7. Zink CF1, Pagnoni G, Martin ME, Dhamala M, Berns GS. Next Section Abstract Although one proposed function of both the striatum and its major dopamine inputs is related to coding rewards and reward-related stimuli, an alternative view suggests a more general role of the striatum in processing salient events, regardless […]

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