Sensitivity to ethanol and other hedonic stimuli in an animal model of adolescence: implications for prevention science? (2010)

Dev Psychobiol. 2010 Apr;52(3):236-43. Spear LP, Varlinskaya EI. Source Department of Psychology, Center for Development and Behavioral Neuroscience, Binghamton University, State University of New York, Binghamton, NY 13902-6000, USA. [email protected] Abstract Age-related patterns of sensitivity to appetitive and aversive stimuli seemingly have deep evolutionary roots, with marked developmental transformations seen during adolescence in a number […]

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Motivational systems in adolescence: possible implications for age differences in substance abuse and other risk-taking behaviors (2010)

Brain Cogn. 2010 Feb;72(1):114-23. Epub 2009 Sep 16.   Doremus-Fitzwater TL, Varlinskaya EI, Spear LP. Source Center for Development and Behavioral Neuroscience, Department of Psychology, Binghamton University, Binghamton, NY 13902-6000, USA. Abstract Adolescence is an evolutionarily conserved developmental phase characterized by hormonal, physiological, neural and behavioral alterations evident widely across mammalian species. For instance, adolescent […]

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The emergence of gonadal hormone influences on dopaminergic function during puberty (2010)

Horm Behav. 2010 Jun;58(1):122-37. Epub 2009 Nov 10.   Kuhn C, Johnson M, Thomae A, Luo B, Simon SA, Zhou G, Walker QD. Source Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA. [email protected] Abstract Adolescence is the developmental epoch during which children become adults-intellectually, physically, hormonally and socially. Brain […]

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(L) Teen brains over-process rewards, suggesting root of risky behavior, mental ills (2011)

 January 26th, 2011 in Medicine & Health / Neuroscience Enlarge  Each row represents the activity in a neuron at key times during the task. At the time of reward, nearly one-third of adolescent neurons became excited (shown in red) though the level of inhibition (in blue) changed marginally. Adult neurons registered much higher inhibitory activity […]

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Developmental Neurocircuitry of Motivation in Adolescence: A Critical Period of Addiction Vulnerability (2003)

Am J Psychiatry. 2003 June; 160(6): 1041–1052.   PMCID: PMC2919168 R. Andrew Chambers, M.D., Jane R. Taylor, Ph.D., and Marc N. Potenza, M.D., Ph.D. Abstract Objective Epidemiological studies indicate that experimentation with addictive drugs and onset of addictive disorders is primarily concentrated in adolescence and young adulthood. The authors describe basic and clinical data supporting […]

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Cognitive Biases toward Internet Game-Related Pictures and Executive Deficits in Individuals with an Internet Game Addiction (2012)

PLoS One. 2012;7(11):e48961. doi: 10.1371/journal.pone.0048961. Epub 2012 Nov 14.   Zhou Z, Yuan G, Yao J. Source Department of Psychology, Wuxi Mental Health Center of Nanjing Medical University, Wuxi City, Jiangsu Province, China. Abstract BACKGROUND: The cue-related go/no-go switching task provides an experimental approach to study individual’s flexibility in changing situations. Because Internet addiction disorder […]

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Internet Addiction: A Brief Summary of Research and Practice. (2012)

Curr Psychiatry Rev. 2012 Nov;8(4):292-298.   PDF -Internet Addiction: A Brief Summary of Research and Practice.   Cash H, Rae CD, Steel AH, Winkler A. Source reSTART Internet Addiction Recovery Program, Fall City, WA 98024. Abstract Problematic computer use is a growing social issue which is being debated worldwide. Internet Addiction Disorder (IAD) ruins lives […]

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Predictability modulates human brain response to reward (2001)

COMMENTS: Unpredictable rewards lead to bigger spikes of dopamine. This is what makes high speed Internet porn different from porn of the past   J Neurosci. 2001 Apr 15;21(8):2793-8.   Berns GS, McClure SM, Pagnoni G, Montague PR. Source Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, USA. [email protected] […]

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Liking and wanting linked to Reward Deficiency Syndrome (RDS): hypothesizing differential responsivity in brain reward circuitry (2012)

Curr Pharm Des. 2012;18(1):113-8. Blum K, Gardner E, Oscar-Berman M, Gold M. FULL STUDY Source Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, FL 32610, USA. [email protected] Abstract In an attempt to resolve controversy regarding the causal contributions of mesolimbic dopamine (DA) systems to reward, we evaluate the three main competing explanatory […]

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