Prog Neuropsychopharmacol Biol Psychiatry. 2019 Dec 17:109847. doi: 10.1016/j.pnpbp.2019.109847.
Balodis IM1, Potenza MN2.
Abstract
Both psychological and neurobiological studies in gambling disorder have increased in the past 10-15 years. This review examines the current state of the literature, with a focus on recent magnetic resonance imaging (MRI) neuroimaging studies in gambling disorder. The review compares and contrasts findings across gambling and substance-use disorders. Additionally, features with arguably particular relevance to gambling disorder (e.g., “near-miss” processing) are described, as well as their relationship to choice behaviors. More broadly, the review informs on how these studies advance our understanding of brain-behavior relationships relating to decision-making and key features of addictive disorders.
KEYWORDS: Addiction; Gambling; Near-miss; Striatum; rTMS
PMID: 31862419